Fig. 4
From: Genome-wide DNA methylome reveals the dysfunction of intronic microRNAs in major psychosis
Relationship between intronic DMRs and functional elements. a, b Heatmaps showing different types of functional elements defined by multiple epigenetic marks at or around hypermethylated and hypomethylated intronic DMRs in SZ (a) and BD (b). c, d Enrichment of hypermethylated and hypomethylated intronic DMRs in transcription factor binding. Each bar represents the O/E ratio between the observed and expected number of intronic DMRs overlapping with the TF binding sites in SZ (c) and BD (d). Asterisks indicating the significance levels (* represents P < 0.05; ** represents P < 0.01)