Fig. 1
Modifiers of the effect of genetic risk estimate on change in perceived risk (ΔPR) of cancer. a. Mean ΔPR of colorectal cancer, stratified by cancer family history status. An average risk result was associated with a non-significant mean ΔPR of −0.002 (95 % CI = −0.12, 0.11) in participants reporting no family history of cancer, and a non-significant mean ΔPR of −0.05 (−0.12, 0.007) in those reporting a positive family history. An elevated risk result was associated with a mean ΔPR of 0.26 (0.06, 0.47) in the absence of family history, and a mean ΔPR of 0.56 (0.45, 0.66) in the presence of a family history (pinteraction = 0.0093). b. Mean ΔPR of lung cancer, stratified by baseline interest in lung cancer risk results. An average risk result was associated with a non-significant mean ΔPR of 0.11 (−0.03, 0.25) in participants who expressed low interest in lung cancer risk information at baseline, and a mean ΔPR of 0.20 (0.11, 0.29) in those who expressed a moderate or high interest in this information at baseline. An elevated risk result was associated with a mean ΔPR of 0.26 (0.01, 0.50) given low interest, and a mean ΔPR of 0.73 (0.59, 0.88) given moderate or high interest (pinteraction = 0.0434). Error bars represent standard error of the mean