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Table 2 Characteristics of PGen study participants included in at least one linear regression analysis for change in perceived risk of cancer

From: The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study

  Breast (n = 641) Prostate (n = 383) Colorectal (n = 1069) Lung (n = 1067)
  No. % No. % No. % No. %
Female gender 641 100.0 0 0.0 646 60.4 647 60.6
Non-white race 90 14.0 43 11.2 145 13.6 144 13.5
Hispanic/latino ethnicity 23 3.6 20 5.2 39 3.7 39 3.7
Highest level of education
 No college degree 152 23.7 64 16.7 224 20.9 223 20.9
 College degree only 194 30.3 121 31.6 327 30.6 326 30.6
 Some graduate school 219 34.2 139 36.3 375 35.1 375 35.1
 Doctoral-level degree 76 11.8 59 15.4 143 13.4 143 13.4
Annual household income
 < $40,000 118 18.4 55 14.4 177 16.5 176 16.5
 $40,000–$69,999 128 20.0 55 14.4 192 17.9 192 18.0
 $70,000–$99,999 135 21.1 75 19.6 223 20.9 223 20.9
 $100,000–$199,999 193 30.1 126 32.9 329 30.9 331 31.0
 ≥ $200,000 58 9.0 66 17.2 133 12.4 130 12.2
 Not reported 9 1.4 6 1.5 15 1.4 15 1.4
Any cancer family history
 Affected FDR(s) 296 46.2 167 43.6 489 45.7 488 45.8
 Affected SDR(s) only 219 34.2 116 30.3 345 32.3 345 32.3
 No affected FDR/SDR(s) 116 18.1 99 25.8 223 20.9 222 20.8
 Not reported 10 1.5 1 0.3 12 1.1 12 1.1
Specific cancer family historya
 Affected FDR(s) 84 13.1 29 7.6 72 6.8 65 6.1
 Affected SDR(s) only 137 21.4 21 5.5 138 12.9 139 13.0
 No affected FDR/SDR(s) 410 64.0 332 86.7 847 79.2 851 79.8
 Not reported 10 1.5 1 0.2 12 1.1 12 1.1
Interest in cancer-specific PGT
 Not at all interested 37 5.8 19 5.0 120 11.2 209 19.6
 Somewhat interested 177 27.6 136 35.5 392 36.7 421 39.5
 Very interested 427 66.6 228 59.5 557 52.1 437 40.9
 Pathway customers 290 45.2 115 30.0 415 38.8 414 38.8
Age, years
 Mean ± standard deviation 46.8 ± 14.9 45.7 ± 16.2 47.1 ± 15.7 47.1 ± 15.7
 Range 19, 92 19, 91 19, 94 19, 94
Baseline perceived riskb
 Mean ± standard deviation 2.8 ± 1.0 2.9 ± 0.9 2.7 ± 1.0 2.3 ± 1.0
 Range 1, 5 1, 5 1, 5 1, 5
  1. FDR first-degree relative, SDR second-degree relative, PGT personal genomic testing
  2. aOnly includes reported cases of the type of cancer being studied
  3. bFor the specific cancer being studied, rated from “much below average” (1) to “much higher than average” (5)
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BMC Medical Genomics

ISSN: 1755-8794

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