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Table 2 Characteristics of PGen study participants included in at least one linear regression analysis for change in perceived risk of cancer

From: The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study

 

Breast (n = 641)

Prostate (n = 383)

Colorectal (n = 1069)

Lung (n = 1067)

 

No.

%

No.

%

No.

%

No.

%

Female gender

641

100.0

0

0.0

646

60.4

647

60.6

Non-white race

90

14.0

43

11.2

145

13.6

144

13.5

Hispanic/latino ethnicity

23

3.6

20

5.2

39

3.7

39

3.7

Highest level of education

 No college degree

152

23.7

64

16.7

224

20.9

223

20.9

 College degree only

194

30.3

121

31.6

327

30.6

326

30.6

 Some graduate school

219

34.2

139

36.3

375

35.1

375

35.1

 Doctoral-level degree

76

11.8

59

15.4

143

13.4

143

13.4

Annual household income

 < $40,000

118

18.4

55

14.4

177

16.5

176

16.5

 $40,000–$69,999

128

20.0

55

14.4

192

17.9

192

18.0

 $70,000–$99,999

135

21.1

75

19.6

223

20.9

223

20.9

 $100,000–$199,999

193

30.1

126

32.9

329

30.9

331

31.0

 ≥ $200,000

58

9.0

66

17.2

133

12.4

130

12.2

 Not reported

9

1.4

6

1.5

15

1.4

15

1.4

Any cancer family history

 Affected FDR(s)

296

46.2

167

43.6

489

45.7

488

45.8

 Affected SDR(s) only

219

34.2

116

30.3

345

32.3

345

32.3

 No affected FDR/SDR(s)

116

18.1

99

25.8

223

20.9

222

20.8

 Not reported

10

1.5

1

0.3

12

1.1

12

1.1

Specific cancer family historya

 Affected FDR(s)

84

13.1

29

7.6

72

6.8

65

6.1

 Affected SDR(s) only

137

21.4

21

5.5

138

12.9

139

13.0

 No affected FDR/SDR(s)

410

64.0

332

86.7

847

79.2

851

79.8

 Not reported

10

1.5

1

0.2

12

1.1

12

1.1

Interest in cancer-specific PGT

 Not at all interested

37

5.8

19

5.0

120

11.2

209

19.6

 Somewhat interested

177

27.6

136

35.5

392

36.7

421

39.5

 Very interested

427

66.6

228

59.5

557

52.1

437

40.9

 Pathway customers

290

45.2

115

30.0

415

38.8

414

38.8

Age, years

 Mean ± standard deviation

46.8 ± 14.9

45.7 ± 16.2

47.1 ± 15.7

47.1 ± 15.7

 Range

19, 92

19, 91

19, 94

19, 94

Baseline perceived riskb

 Mean ± standard deviation

2.8 ± 1.0

2.9 ± 0.9

2.7 ± 1.0

2.3 ± 1.0

 Range

1, 5

1, 5

1, 5

1, 5

  1. FDR first-degree relative, SDR second-degree relative, PGT personal genomic testing
  2. aOnly includes reported cases of the type of cancer being studied
  3. bFor the specific cancer being studied, rated from “much below average” (1) to “much higher than average” (5)