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Table 2 List of most highly ranked genes based on Authority or Hub scores

From: Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12

A

 

Rank

Authorities

 1

NLRP1

 2

BIRC3

 3

EIF4A1

 4

FAS

 5

CFLAR

 6

TNFRSF9

 7

PTPRCAP

 8

EGR3

 9

IFNG

B

 

Rank

Hubs

 1

CASP1

 2

FASLG

 3

TRAF1

 4

NFKB1

 5

NFKBIA

 6

TNFRSF1B

 7

FAS

 8

IL11RA

 9

PTPRC

  1. The HITS algorithm was used to measure two important characteristics of an overall genomic network: the authority of individual genes, which may be interpreted as a surrogate marker for the relative “importance” of those genes to the overall function of the network (Table 2a); and the hub value of individual genes, which is a surrogate marker for the relative “impact” of that gene on the interconnections or relationships between genes that make up that same network (Table 2b). Authority and Hub scores are presented in decreasing order within the integrated network