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Table 1 Overview of database annotations

From: The HAND Database: a gateway to understanding the role of HIV in HIV-associated neurocognitive disorders

Category

Annotation

Example

Explanation

Patient

Patient: Code

SUBJECT_4

The originating publication ID for this patient was “SUBJECT_4”

Patient

Patient: HAND Status

HIVE + ADC

This patient had two forms of HAND: HIVE and ADC

Patient

Patient: Sex

M

This patient was male

Patient

Patient: Risk Factor

IV Drug User

This patient may have contracted the HIV virus through IV drug use

Patient

Patient: Viral Load At Sampling

Unknown Viral Load

Information on this patient’s viral load at time of sampling could not be found

Patient

Patient: CD4 Count At Sampling

5 cells/ul

This patient had a CD4 count of 5 cells/ul at time of sampling

Patient

Patient: HIV Therapy Status

AZT

This patient had received AZT therapy prior to sampling

Patient

Patient: HIV Therapy Months

20

This patient had received HIV therapy for 20 months prior to sampling

Patient

Patient: Age At Sampling

29

This patient was 29 years of age at time of sampling

Patient

Patient: Health At Sampling

AIDS

This patient had AIDS at time of sampling

Sampling

Sampling: Year

1993

This sample was obtained in the year 1993

Sampling

Sampling: Country (City)

Japan (unknown)

This sample was obtained in an unknown city in the country of Japan

Sampling

Sampling: Tissue

Spleen

This sample was obtained from spleen tissue

Sequence

Sequence: Polyprotein (Protein)

Tat (gp160)

This sequence segment covers the Tat and Gp160 HIV regions

Sequence

Sequence: Genotyping Information1

B (B)*

This sequence was listed by the originating data source as a B subtype sequence. jpHMM genotyping confirmed subtype as B. Recombination testing detected recombination events in this sequence (indicated by the asterisk).

Sequence

Sequence: Accession Number

U82096

The sequence accession number for this sequence is U82096

Sequence

Sequence: PMID

9718130

The sequence PMID for this sequence is 9718130

Sequence

Sequence: Length in Nucleotides

150

The sequence length for this sequence segment is 150 nucleotides

Sequence

HIV Sequence

cccaaat…

The nucleotide sequence for this sequence is “cccaaat…”

  1. 1The sequence genotyping annotation provides genotyping and recombination information in the following format: Subtype as reported in the original source material (Subtype as reported by jpHMM genotyping) and recombination information. Additional symbols used in this annotation include: “#” = not tested due to insufficient length of sequence, “*” = p < 0.05 for recombination test, “(No)” = p > 0.05 for recombination test