Table 1 Patient and sample information
From: DNA methylation subgroups in melanoma are associated with proliferative and immunological processes
Feature | Bergen (n = 50) | TCGA (n = 242) |
|---|---|---|
Gender | ||
Male | 28 (56) | 154 (64) |
Female | 22 (44) | 88 (36) |
Median thickness (mm) | 2.25 (0.5-25) | 2.7 (0.28-50) |
Clark | ||
I | 3 (9) | 3 (2) |
II | 2 (6) | 13 (7) |
III | 9 (27) | 49 (27) |
IV | 13 (39) | 83 (46) |
V | 6 (18) | 31 (17) |
Histogroup | ||
SSM | 18 (53) | - |
NM | 16 (47) | - |
Sample origin | ||
Primary | 0 | 27 (11) |
Regional LN | 3 (6) | 134 (56) |
Regional other | 0 | 49 (20) |
Distant metastasis | 47 (94) | 31 (13) |
BRAF mutation | ||
yes | 25 (50) | 118 (49) |
no | 25 (50) | 123 (51) |
NRAS mutation | ||
yes | 11 (22) | 66 (27) |
no | 39 (78) | 175 (73) |
CDKN2A-arrayCGH | ||
Homozygous Deletion | 11 (22) | - |
Present | 39 (78) | - |
Gene expression phenotype | ||
High-immune | 15 (30) | 69 (32) |
Normal-like | 3 (6) | 33 (15) |
Pigmentation | 20 (40) | 63 (29) |
Proliferative | 12 (24) | 49 (23) |