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Table 1 Gene characteristics used in the analysis to estimate if they are associated with efficacy of prediction of gene expression in lung based on gene expression in blood

From: Prediction of the gene expression in normal lung tissue by the gene expression in blood

Trait

Statistic

P-Value

Method

Nuclear localization of the gene product

0.04

0.00001

Kolmogorov-Smirnov

Size of the gene region in nucleotides

4.37

0.00009

Spearman’s

Number of exons in the gene

5.92

0.00521

Spearman’s

PTMa (ubiquitination)

0.02

0.00573

Kolmogorov-Smirnov

PTM (acetylation)

0.03

0.01269

Kolmogorov-Smirnov

PTM (methylation)

0.04

0.01735

Kolmogorov-Smirnov

Plasma membrane localization of the gene product

0.03

0.08340

Kolmogorov-Smirnov

Receptor

0.03

0.10019

Kolmogorov-Smirnov

Signal transducer

0.03

0.12617

Kolmogorov-Smirnov

Nuclear membrane localization

0.09

0.12746

Kolmogorov-Smirnov

Kinase

0.06

0.17557

Kolmogorov-Smirnov

Extracellular localization

0.03

0.20352

Kolmogorov-Smirnov

Growth factor

0.09

0.22230

Kolmogorov-Smirnov

Phosphatase

0.10

0.23498

Kolmogorov-Smirnov

PTM (sumoylation)

0.06

0.24742

Kolmogorov-Smirnov

Conservation Index of the gene

4.56

0.31737

Spearman’s

Secreted gene product

0.02

0.34382

Kolmogorov-Smirnov

Transcription factor

0.02

0.39715

Kolmogorov-Smirnov

PTM (phosphorylation)

0.01

0.61248

Kolmogorov-Smirnov

Housekeeping gene

0.03

0.68928

Kolmogorov-Smirnov

Tissue specific gene expression

0.01

0.76322

Kolmogorov-Smirnov

Cytoplasmic localization of the gene product

0.01

0.92317

Kolmogorov-Smirnov

  1. a PTM Post Translational Modifications