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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Fig. 1

Identification of molecular drivers of HDM-driven gene expression patterns in CD4 T cells. Differentially expressed genes/molecular drivers were identified in: a/d HDM-sensitized atopics with asthma; b/e HDM-sensitized atopics without asthma; and c/f HDM-nonsensitized controls. Data analysis was performed by LIMMA (a, b, c) and upstream regulator analysis (d, e, f). The dashed horizontal line in figs a, b, c indicates FDR <0.05. Drivers in red are predicted to be activated and those in blue are inhibited

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