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Table 2 Disease enrichment analysis on the Genetic Association Database of a set of 134 genes prioritized for PD by using Limma

From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization

GAD Term p-Value Hits Sample Total Sample Hits Background Total Background
bipolar disorder 0.0030 7 39 96 2459
schizophrenia 0.0034 11 39 249 2459
alcohol abuse 0.0227 4 39 40 2459
Parkinson’s disease 0.0271 6 39 112 2459
delinquent behavior violent behavior 0.0307 2 39 2 2459
schizophrenia; opium abuse 0.0307 2 39 2 2459
alcoholism 0.0346 4 39 47 2459
nicotine dependence smoking behavior 0.0457 2 39 3 2459
impulsivity 0.0457 2 39 3 2459
bipolar affective disorder; unipolar affective disorder 0.0457 2 39 3 2459
personality traits 0.0480 3 39 23 2459
  1. Hits Sample: Number of genes selected by Limma that are asociated with the disease condition; Total Sample: Number of genes selected by Limma; Hits Background: Number of genes in the background that are asociated with the disease condition; Total Background: Number of genes in the background
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