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Table 6 Hypergeometric test results for the WGCN PD modules based on 319 known PD related genes in GAD and 8477 background genes

From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization

Prioritized PD Module

n

m

p-value

PD_01

603

29

0.1014

PD_02

1437

73

0.0034

PD_03

133

6

0.3849

PD_04

161

6

0.5685

PD_05

789

19

0.9897

PD_06

468

15

0.7776

PD_07

494

26

0.0512

PD_08

213

10

0.2813

PD_09

4179

128

0.9997

PD_02 PD_07

1931

99

0.0003

  1. n: number or genes in the prioritized PD module; m: number of known PD related genes in GAD found in the prioritized module; p-value: hypergeometric probability of finding by chance k or more known PD related genes in a set of n prioritized genes