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Table 8 Overall enrichment and early recognition metrics of the four prioritization strategies considered

From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization

  Limma ML ML-Limma Consensus
Classic Enrichment Metrics
AUAC 0.498 0.502 0.495 0.540
ROC 0.498 0.502 0.495 0.541
EF 1% 2.855 2.521 2.847 3.164
EF 5% 1.449 1.387 1.007 1.512
EF 10% 1.038 1.385 0.913 1.510
EF 20% 0.975 1.054 1.054 1.321
Early Recognition Metrics
RIE 1% 2.452 2.213 2.403 2.577
RIE 5% 1.286 1.438 1.157 1.583
RIE 10% 1.089 1.225 1.044 1.400
RIE 20% 1.021 1.085 1.008 1.230
BEDROC 1% 0.094 0.086 0.094 0.099
BEDROC 5% 0.091 0.102 0.083 0.113
BEDROC 10% 0.131 0.147 0.125 0.168
BEDROC 20% 0.216 0.230 0.214 0.262
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