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Table 9 Results of the Wilcoxon signed rank test conducted to compare the ranking provided by the four approaches under study

From: Efficient and biologically relevant consensus strategy for Parkinson’s disease gene prioritization

319 PD Genes in GAD (100 %)

 

Limma

ML

ML-Limma

Consensus

 Limma

(−−−)

2.62E-09

2.85E-01

2.79E-62

 ML

2.62E-09

(−−−)

1.16E-01

4.36E-47

 ML-Limma

2.85E-01

1.16E-01

(−−−)

4.27E-64

 Consensus

2.79E-62

4.36E-47

4.27E-64

(−−−)

64 Top Ranked PD Genes in GAD (Top 20 %)

 

Limma

ML

ML-Limma

Consensus

 Limma

(−−−)

1.84E-05

6.09E-01

6.81E-09

 ML

1.84E-05

(−−−)

1.21E-07

1.69E-06

 ML-Limma

6.09E-01

1.21E-07

(−−−)

1.24E-12

 Consensus

6.81E-09

1.69E-06

1.24E-12

(−−−)

32 Top Ranked PD Genes in GAD (Top 10 %)

 

Limma

ML

ML-Limma

Consensus

 Limma

(−−−)

7.19E-01

5.23E-04

1.19E-02

 ML

7.19E-01

(−−−)

7.25E-02

3.11E-02

 ML-Limma

5.23E-04

7.25E-02

(−−−)

1.38E-05

 Consensus

1.19E-02

3.11E-02

1.38E-05

(−−−)

16 Top Ranked PD Genes in GAD (Top 5 %)

 

Limma

ML

ML-Limma

Consensus

 Limma

(−−−)

6.06E-01

4.23E-01

3.02E-01

 ML

6.06E-01

(−−−)

3.02E-01

1.95E-03

 ML-Limma

4.23E-01

3.02E-01

(−−−)

4.33E-02

 Consensus

3.02E-01

1.95E-03

4.33E-02

(−−−)