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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

Fig. 2

RPL5 is required for both primitive hematopoiesis and definitive hematopoiesis, which are partially mediated the by P53 pathway in zebrafish. a-c The expression of scl was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 12 hpf. d-i The expression of gata1 and pu1 was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 12 hpf. j-o The expression of c-myb and runx1 was significantly decreased in RPL5 MO zebrafish and was partly rescued in RPL5 and P53 double MO zebrafish at 48 hpf

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