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Table 1 Pathways enriched by regulated genes (fold-change > 2 and p-value < 0.05) in RPL5 MO

From: Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

Expression Pattern

KEGG Pathway

Count

P-Value

Up-regulated

Ribosome

10

1.90E-05

Down-regulated

Spliceosome

25

2.80E-07

Down-regulated

Cell cycle

26

4.00E-07

Down-regulated

DNA replication

10

4.40E-04

Down-regulated

Aminoacyl-tRNA biosynthesis

9

1.70E-03

Down-regulated

Notch signaling pathway

11

2.20E-03

Down-regulated

Base excision repair

7

1.80E-02

Down-regulated

Lysine degradation

8

1.90E-02

Down-regulated

RNA degradation

9

3.00E-02