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Table 3 Relationship between awareness of the benefit of genome study and awareness of the Nagahama study, self-rated understanding of terminology, concern, and belief of usage of genetic information in companies or government bodies from Logistic Regression Analysis

From: Experiences and attitudes of residents regarding a community-based genome cohort study in Japan: a population-based, cross-sectional study

  Male (n=704) Female (n=769)
The use of genetic information is helpful for disease treatment   The use of genetic information is helpful for disease treatment  
Agree (n=554) Neutral or Disagree ORa 95 % CI P-value Agree (n=591) Neutral or Disagree ORa 95 % CI P-value
n (%) n (%)     n (%) n (%)    
High awareness of the Nagahama study 191 (34.8) 14 (12.4) 3.82 1.93–7.57   326 (55.6) 40 (33.3) 2.63 1.63–4.24 <0.001
Self-rated understanding of terminology
 High 231 (41.8) 19 (16.5) 1    168 (28.8) 15 (12.6) 1   
 Middle 206 (37.3) 30 (26.1) 0.66 0.34–1.29 0.223 224 (38.4) 37 (31.1) 0.72 0.36–1.42 0.342
 Low 116 (21.0) 66 (57.4) 0.24 0.12–0.46 <0.001 192 (32.9) 67 (56.3) 0.49 0.27–0.98 0.045
Concerns
 Financial infusion 456 (84.0) 60 (52.2) 4.37 2.49–7.69 <0.001 473 (81.4) 65 (53.7) 2.98 1.79–4.97 <0.001
 Privacy concerns 343 (62.5) 56 (49.6) 0.72 0.39–1.32 0.284 335 (56.9) 53 (43.8) 1.00 0.57–1.74 0.993
 Discriminations 250 (45.3) 39 (34.2) 1.38 0.74–2.58 0.315 234 (39.9) 38 (31.4) 0.77 0.43–1.38 0.386
 Unexpected negative effects 228 (41.4) 38 (33.0) 1.02 0.54–1.93 0.963 192 (32.6) 33 (27.5) 0.49 0.26–0.90 0.022
 Cloned human beings 203 (37.0) 35 (30.4) 0.87 0.46–1.66 0.682 191 (32.5) 24 (20.2) 2.27 1.16–4.46 0.017
Belief
 Company or government bodies use genome information 267 (48.8) 33 (29.7) 1.35 0.77–2.36 0.299 251 (42.7) 30 (25.0) 1.71 0.98–3.00 0.060
  1. aAdjusted according to age and formal education duration