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Table 1 Demographic characteristics. Demographic characteristics of 101 pregnant women in Mirae & Heemang, Namujungwon, and GN hospitals in Korea

From: Comparison of two high-throughput semiconductor chip sequencing platforms in noninvasive prenatal testing for Down syndrome in early pregnancy

Demographic characteristics Euploid (n = 96) T21 (n = 5) P value Total (n = 101)
Maternal age, years, mean ± SD 35.55 ± 3.63 33.40 ± 3.64   35.45 ± 3.64
≥35 years (%) 59 (61.46) 1(20.00)   60 (59.41)
NIPT during gestational week 11–13 (%) 67 (69.79) 3 (60.0)   70 (69.31)
NIPT during gestational week 14–18 (%) 29 (30.21) 2 (40.0)   31 (30.69)
PGM, z-score of chr21 (min, max) −3.46, 2.07 5.50, 9.43 <0.0001† −3.46, 9.43
Proton, z-score of chr21 (min, max) −2.32, 2.10 6.20, 8.86 <0.0001† −2.32, 8.96
  1. T21 Trisomy 21, SD standard deviation, NIPT non-invasive prenatal testing. P values from †Student’s t-test