Comparison of two high-throughput semiconductor chip sequencing platforms in noninvasive prenatal testing for Down syndrome in early pregnancy

Table 3 Comparison of both Ion chips. Comparison of PGM and Proton semiconductor-based Ion chips using five different factors

Chip type	Total reads		Read mapped ratio		Mean read length		Phred quality score (≥Q20)		Correlation
Chip type	Average	SD/average	Average	SD	Average	SD	Average	SD	Coefficient	Significance
318 of PGM	4512893	0.2823	99.078	0.6635	147.871	10.693	0.8611	0.0374	0.9704	P < 0.0001
PI of Proton	7572314	0.1837	99.011	1.1470	147.842	5.669	0.8537	0.0225	0.9813	P < 0.0001

ISSN: 1755-8794