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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Study design and data analysis considerations for the discovery of prognostic molecular biomarkers: a case study of progression free survival in advanced serous ovarian cancer

Fig. 3

a Scatter plot of marker-specific standard deviations versus marker-specific means for the selection of well-expressed and poorly-expressed miRNAs. b Histogram of the Pearson correlation coefficients among the collection of unique markers for each poorly-expressed miRNA, before (top panel) and after (bottom panel) quantile normalization. c Histogram of the Pearson correlation coefficients calculated among replicate markers for each well-expressed miRNA, before (top panel) and after (bottom panel) quantile normalization

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