Fig. 2From: Frequent hypermethylation of orphan CpG islands with enhancer activity in cancerEpigenetic marks reveal that the eCGIs have enhancer signatures. Distribution of epigenetic marks spanning 5Â kb from the center of the eCGIs, typical enhancers, and pCGIs, respectively. P300 and Pol2 are closely related to enhancer activity a, b and H3K4 methylations are known as enhancer c, d or promoter e markersBack to article page