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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Integrative approach for inference of gene regulatory networks using lasso-based random featuring and application to psychiatric disorders

Fig. 1

Example of network structures. a Feed-forward loops and b Cascades. When G3 is a target gene, G1 →G3 and G2 →G3 of Cascades are indirect and direct regulations respectively. In MI-based methods, indirect regulations are likely to be selected incorrectly in Cascades. In regression based method, strong direct regulators are more likely to be selected than another direct regulator in Feed-forward loops

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