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Table 1 Demographic and clinical characteristics of pediatric and adult celiac disease

From: Shared and unique common genetic determinants between pediatric and adult celiac disease

Variables Pediatric CD patients (n = 531) Adults CD patients (n = 871) P value
Mean ± SD age (in years) 10.08 ± 4.60 35.34 ± 11.83 NA
Gender    
 Male
 Female
290 (54.61)
241 (45.40)
345 (39.60)
526 (60.40)
1 × 10 −3
1 × 10 −3
Presentation    
• Classical
• Non-classical
• Screening
401 (75.50)
108 (20.30)
22 (4.20)
606 (69.60)
220 (25.20)
45 (5.20)
0.01
0.02
0.13
Associated diseases    
 Iron deficiency anaemia
 Short stature
 Osteoporosis
 Raised transaminases
 Autoimmune hepatitis
 Infertility
 Hypothyroidism
 Type 1 diabetes
 Sjogren’s syndrome
 Dermatitis herpetiformis
 Idiopathic seizure
 Down’s syndrome
 Inflammatory bowel disease
 Alopecia areata
 Rheumatoid arthritis
 Vitiligo
 Primary biliary cirrhosis
72(13.20)
17 (3.20)
0 (0.00)
28(5.27)
03(0.56)
NA(0.00)
02(0.38)
05(0.94)
0(0.00)
0(0.00)
01(0.19)
01(0.19)
01(0.19)
01(0.19)
0(0.00)
0(0.00)
0(0.00)
167 (19.20)
37(4.25)
06(0.69)
58(6.60)
06(0.69)
03(0.34)
17(1.95)
03(0.34)
05(0.57)
03(0.34)
06(0.69)
02(0.23)
03(0.34)
0(0.00)
3(0.34)
3(0.34)
3(0.34)
0.01
0.17
0.05
0.16
0.59
0.12
0.04
0.12
0.10
0.12
0.13
0.82
0.31
0.13
0.12
0.12
0.12
Complications    
 Celiac crisis
 Refractory CD
 Malignancy
----
----
----
04 (0.5)
02 (0.3)
04 (0.5)
1 × 10 −3
1 × 10 −3
1 × 10 −3
Mean titre of anti-tTG antibody (U/L) 130.00 118.60 1 × 10 −3
Grade of villous abnormalities (Modified Marsh classification)    
 I/II
 IIIa
 IIIb
 IIIc
26 (4.63)
44 (8.28)
115 (21.65)
346 (65.16)
92 (10.56)
139 (15.95)
170 (19.51)
470 (53.96)
7 × 10 −3
6 × 10 −3
0.17
6 × 10 −3
  1. NA not applicable, The values presented in parenthesis is a percentages
  2. Bolds (P values) are the significant associations (p ≤ 0.05)