Table 1 Demographic and clinical characteristics of pediatric and adult celiac disease
From: Shared and unique common genetic determinants between pediatric and adult celiac disease
Variables | Pediatric CD patients (n = 531) | Adults CD patients (n = 871) | P value |
|---|---|---|---|
Mean ± SD age (in years) | 10.08 ± 4.60 | 35.34 ± 11.83 | NA |
Gender | Â | Â | Â |
 Male  Female | 290 (54.61) 241 (45.40) | 345 (39.60) 526 (60.40) | 1 × 10 −3 1 × 10 −3 |
Presentation | Â | Â | Â |
• Classical • Non-classical • Screening | 401 (75.50) 108 (20.30) 22 (4.20) | 606 (69.60) 220 (25.20) 45 (5.20) | 0.01 0.02 0.13 |
Associated diseases | Â | Â | Â |
 Iron deficiency anaemia  Short stature  Osteoporosis  Raised transaminases  Autoimmune hepatitis  Infertility  Hypothyroidism  Type 1 diabetes  Sjogren’s syndrome  Dermatitis herpetiformis  Idiopathic seizure  Down’s syndrome  Inflammatory bowel disease  Alopecia areata  Rheumatoid arthritis  Vitiligo  Primary biliary cirrhosis | 72(13.20) 17 (3.20) 0 (0.00) 28(5.27) 03(0.56) NA(0.00) 02(0.38) 05(0.94) 0(0.00) 0(0.00) 01(0.19) 01(0.19) 01(0.19) 01(0.19) 0(0.00) 0(0.00) 0(0.00) | 167 (19.20) 37(4.25) 06(0.69) 58(6.60) 06(0.69) 03(0.34) 17(1.95) 03(0.34) 05(0.57) 03(0.34) 06(0.69) 02(0.23) 03(0.34) 0(0.00) 3(0.34) 3(0.34) 3(0.34) | 0.01 0.17 0.05 0.16 0.59 0.12 0.04 0.12 0.10 0.12 0.13 0.82 0.31 0.13 0.12 0.12 0.12 |
Complications | Â | Â | Â |
 Celiac crisis  Refractory CD  Malignancy | ---- ---- ---- | 04 (0.5) 02 (0.3) 04 (0.5) | 1 × 10 −3 1 × 10 −3 1 × 10 −3 |
Mean titre of anti-tTG antibody (U/L) | 130.00 | 118.60 | 1 × 10 −3 |
Grade of villous abnormalities (Modified Marsh classification) | Â | Â | Â |
 I/II  IIIa  IIIb  IIIc | 26 (4.63) 44 (8.28) 115 (21.65) 346 (65.16) | 92 (10.56) 139 (15.95) 170 (19.51) 470 (53.96) | 7 × 10 −3 6 × 10 −3 0.17 6 × 10 −3 |