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Table 2 Top association signals identified in Pediatric CD and their association status in Adult CD among north Indians patients

From: Shared and unique common genetic determinants between pediatric and adult celiac disease

Pediatric CD Adult CD  
SNPs (RA) RAF OR P OR P Position Ref Seq genes
rs2854275 T 0.15 6.22[4.52–8.57] 4.28 × 10−29 6.11[4.58–8.15] 5.82 × 10−35 intronic HLA-DQB1
rs4948256 A 0.22 1.90[1.46–2.48] 2.06 × 10−6 1.50[1.18–1.90] 1 × 10−3 intronic ANK3
rs1322423 G 0.87 2.49[1.58–3.94] 8.75 × 10−5 1.05[0.77–1.41] 0.77 694 kb 3’ TSG1
rs4925813 G 0.51 1.64[1.28–2.10] 1.03 × 10−4 1.28[1.04–1.58] 0.02 17 kb 5’ ARHGAP39
rs956506 T 0.23 1.68[1.28–2.20] 1.79 × 10−4 1.20[0.94–1.54] 0.14 intronic MACROD2
rs2981579 C 0.57 1.60[1.25–2.08] 2.54 × 10−4 1.05[0.85–1.29] 0.64 intronic FGFR2
rs4806741 G 0.12 1.84[1.32–2.56] 3.17 × 10−4 1.41[1.03–1.94] 0.03 6.1 kb 5' LILRA3
rs854680 T 0.29 1.58[1.23–2.04] 3.60 × 10−4 1.09[0.87–1.37] 0.45 527 bp 5' CCL16
rs4692386 T 0.50 1.56[1.22–1.99] 3.64 × 10−4 0.93[0.75–1.15] 0.50 189 kb 5' RBPJ
rs9300549 G 0.61 1.64[1.25–2.14] 3.64 × 10−4 0.85[0.68–1.06] 0.16 145 kb 5' GRP183
rs4857943 G 0.29 1.57[1.22–2.01] 3.83 × 10−4 1.20[0.95–1.50] 0.12 178 kb 3' SGOL1
rs10503653 C 0.27 1.60[1.23–2.07] 3.87 × 10−4 1.27[1.01–1.60] 0.05 intronic CSGALNACT1
rs2061737 G 0.51 1.58[1.23–2.03] 3.89 × 10−4 0.91[0.74–1.23] 0.38 3q26.1 N/A
  1. RA risk allele, RAF risk allele frequency in controls