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Table 2 Top association signals identified in Pediatric CD and their association status in Adult CD among north Indians patients

From: Shared and unique common genetic determinants between pediatric and adult celiac disease

Pediatric CD

Adult CD

 

SNPs

(RA)

RAF

OR

P

OR

P

Position

Ref Seq genes

rs2854275

T

0.15

6.22[4.52–8.57]

4.28 × 10−29

6.11[4.58–8.15]

5.82 × 10−35

intronic

HLA-DQB1

rs4948256

A

0.22

1.90[1.46–2.48]

2.06 × 10−6

1.50[1.18–1.90]

1 × 10−3

intronic

ANK3

rs1322423

G

0.87

2.49[1.58–3.94]

8.75 × 10−5

1.05[0.77–1.41]

0.77

694 kb 3’

TSG1

rs4925813

G

0.51

1.64[1.28–2.10]

1.03 × 10−4

1.28[1.04–1.58]

0.02

17 kb 5’

ARHGAP39

rs956506

T

0.23

1.68[1.28–2.20]

1.79 × 10−4

1.20[0.94–1.54]

0.14

intronic

MACROD2

rs2981579

C

0.57

1.60[1.25–2.08]

2.54 × 10−4

1.05[0.85–1.29]

0.64

intronic

FGFR2

rs4806741

G

0.12

1.84[1.32–2.56]

3.17 × 10−4

1.41[1.03–1.94]

0.03

6.1 kb 5'

LILRA3

rs854680

T

0.29

1.58[1.23–2.04]

3.60 × 10−4

1.09[0.87–1.37]

0.45

527 bp 5'

CCL16

rs4692386

T

0.50

1.56[1.22–1.99]

3.64 × 10−4

0.93[0.75–1.15]

0.50

189 kb 5'

RBPJ

rs9300549

G

0.61

1.64[1.25–2.14]

3.64 × 10−4

0.85[0.68–1.06]

0.16

145 kb 5'

GRP183

rs4857943

G

0.29

1.57[1.22–2.01]

3.83 × 10−4

1.20[0.95–1.50]

0.12

178 kb 3'

SGOL1

rs10503653

C

0.27

1.60[1.23–2.07]

3.87 × 10−4

1.27[1.01–1.60]

0.05

intronic

CSGALNACT1

rs2061737

G

0.51

1.58[1.23–2.03]

3.89 × 10−4

0.91[0.74–1.23]

0.38

3q26.1

N/A

  1. RA risk allele, RAF risk allele frequency in controls