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Table 3 Top association signals identified in Adult CD group and their association status in Pediatric CD among north Indians

From: Shared and unique common genetic determinants between pediatric and adult celiac disease

Adult CD Pediatric CD  
SNPs (RA) RAF OR P OR P Position Ref Seq genes
rs2854275 T 0.15 6.11[4.58–8.15] 5.82 × 10−35 6.22[4.52–8.57] 4.28 × 10−29 intronic HLA-DQB1
rs2788057 T 0.44 1.56[1.27–1.92] 2.29 × 10−5 1.20[0.95–1.53] 0.13 intronic NMNAT2
rs11119390 C 0.74 1.72[1.33–2.23] 3.83 × 10−5 1.14[0.86–1.49] 0.36 intronic MAPKAPK2
rs9359383 G 0.14 1.82[1.37–2.42] 4.05 × 10−5 1.39[0.99–1.94] 0.06 12 kb 5’ LCA5
rs11074015 T 0.45 1.55[1.25–1.92] 7.86 × 10−5 1.01[0.80–1.28] 0.93 126.6 kb 5' SLCO3A1
rs422999 C 0.19 1.65[1.29–2.12] 8.21 × 10−5 1.34[1.00–1.78] 0.05 intronic VAV2
rs1875897 G 0.57 1.56[1.25–1.95] 1.06 × 10−4 1.17[0.91–1.50] 0.22 intronic CSMD1
rs2332094 A 0.12 1.79[1.33–2.41] 1.28 × 10−4 1.27[0.88–1.82] 0.20 8.6 kb 5' KIAA0247
rs11220082 C 0.32 1.53[1.23–1.90] 1.38 × 10−4 1.04[0.81–1.35] 0.76 intronic FEZ1
rs1999594 C 0.33 1.52[1.22–1.88] 1.68 × 10−4 1.11[0.86–1.43] 0.40 20.4 kb 3' KIAA2013
rs1870162 C 0.08 1.85[1.33–2.55] 2.17 × 10−4 N/A N/A intronic GRID1
rs35164067 A 0.20 1.60[1.25–2.06] 2.28 × 10−4 1.23[0.92–1.65] 0.17 6.1 kb 5' PDE4A
rs17463487 T 0.65 1.53[1.22–1.92] 2.23 × 10−4 1.10[0.85–1.41] 0.47 131.6 kb 3' ZNF326
rs6720771 G 0.86 1.73[1.29–2.32] 2.42 × 10−4 1.16[0.85–1.59] 0.34 intronic GALNT13
rs10141085 G 0.18 1.62[1.25–2.10] 2.44 × 10−4 0.95[0.69–1.31] 0.77 intronic KIAA0391
rs4897233 G 0.40 1.49[1.20–1.84] 2.50 × 10−4 1.24[0.97–1.58] 0.09 intronic THEMIS
rs1399357 C 0.51 1.49[1.20–1.85] 2.56 × 10−4 1.29[1.01–1.64] 0.04 363 kb 3' FAM181B
rs963872 C 0.42 1.48[1.19–1.83] 3.38 × 10−4 1.32[1.03–1.69] 0.03 5p15.33 N/A
rs10994257 T 0.26 1.51[1.20–1.90] 4.00 × 10−4 1.62[1.25–2.09] 2.48 × 10−4 intronic ANK3
rs12730072 T 0.09 1.76[1.29–2.41] 4.10 × 10−4 1.67[1.14–2.42] 8 × 10−3 229 bp 5' ITLN2
  1. RA risk allele, RAF risk allele frequency in controls