Table 3 Top association signals identified in Adult CD group and their association status in Pediatric CD among north Indians

rs2854275

T

6.11[4.58–8.15]

5.82 × 10⁻³⁵

6.22[4.52–8.57]

4.28 × 10⁻²⁹

intronic

HLA-DQB1

rs2788057

T

1.56[1.27–1.92]

2.29 × 10⁻⁵

1.20[0.95–1.53]

0.13

intronic

NMNAT2

rs11119390

C

1.72[1.33–2.23]

3.83 × 10⁻⁵

1.14[0.86–1.49]

0.36

intronic

MAPKAPK2

rs9359383

G

1.82[1.37–2.42]

4.05 × 10⁻⁵

1.39[0.99–1.94]

0.06

12 kb 5’

LCA5

rs11074015

T

1.55[1.25–1.92]

7.86 × 10⁻⁵

1.01[0.80–1.28]

0.93

126.6 kb 5'

SLCO3A1

rs422999

C

1.65[1.29–2.12]

8.21 × 10⁻⁵

1.34[1.00–1.78]

0.05

intronic

VAV2

rs1875897

G

1.56[1.25–1.95]

1.06 × 10⁻⁴

1.17[0.91–1.50]

0.22

intronic

CSMD1

rs2332094

A

1.79[1.33–2.41]

1.28 × 10⁻⁴

1.27[0.88–1.82]

0.20

8.6 kb 5'

KIAA0247

rs11220082

C

1.53[1.23–1.90]

1.38 × 10⁻⁴

1.04[0.81–1.35]

0.76

intronic

FEZ1

rs1999594

C

1.52[1.22–1.88]

1.68 × 10⁻⁴

1.11[0.86–1.43]

0.40

20.4 kb 3'

KIAA2013

rs1870162

C

1.85[1.33–2.55]

2.17 × 10⁻⁴

N/A

N/A

intronic

GRID1

rs35164067

A

1.60[1.25–2.06]

2.28 × 10⁻⁴

1.23[0.92–1.65]

0.17

6.1 kb 5'

PDE4A

rs17463487

T

1.53[1.22–1.92]

2.23 × 10⁻⁴

1.10[0.85–1.41]

0.47

131.6 kb 3'

ZNF326

rs6720771

G

1.73[1.29–2.32]

2.42 × 10⁻⁴

1.16[0.85–1.59]

0.34

intronic

GALNT13

rs10141085

G

1.62[1.25–2.10]

2.44 × 10⁻⁴

0.95[0.69–1.31]

0.77

intronic

KIAA0391

rs4897233

G

1.49[1.20–1.84]

2.50 × 10⁻⁴

1.24[0.97–1.58]

0.09

intronic

THEMIS

rs1399357

C

1.49[1.20–1.85]

2.56 × 10⁻⁴

1.29[1.01–1.64]

0.04

363 kb 3'

FAM181B

rs963872

C

1.48[1.19–1.83]

3.38 × 10⁻⁴

1.32[1.03–1.69]

0.03

5p15.33

N/A

rs10994257

T

1.51[1.20–1.90]

4.00 × 10⁻⁴

1.62[1.25–2.09]

2.48 × 10⁻⁴

intronic

ANK3

rs12730072

T

1.76[1.29–2.41]

4.10 × 10⁻⁴

1.67[1.14–2.42]

8 × 10⁻³

229 bp 5'

ITLN2