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Fig. 3 | BMC Medical Genomics

Fig. 3

From: A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

Fig. 3

a FDA approved indications of predicted drug candidates; b Half maximal inhibitory concentration (IC50) (μM) of predicted drug candidates and Doxorubicin against MCF7, SUM149 and MCF10A; c and d Therapeutic index (TI) and maximal inhibitory concentrations (Emax) of predicted repositioned drug candidates on MCF7, SUM149 and MCF10A. (*Currently used FDA drug for breast cancer; Therapeutic index (TI) was calculated as a ratio of the IC50 of MCF10A, to the IC50 of MCF7 and SUM149)

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