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Table 3 Univariate and multivariate cox proportional hazard regression analyses

From: A 19-Gene expression signature as a predictor of survival in colorectal cancer

Genes Univariate Multivariate
  Hazard ratio (95 % CI) p-value Hazard ratio (95 % CI) p-value
NOTCH2 1.356 (1.154 – 1.592) 0.000 *** 1.56 (1.034 – 1.913) 0.009 **
ITPRIP 1.063 (0.919 – 1.23) 0.408 0.852 (0.614 – 1.183) 0.340
FRMD6 1.259 (1.092 – 1.452) 0.001 ** 1.066 (0.850 – 1.338) 0.575
GFRA4 0.860 (0.728 – 1.016) 0.005 ** 0.871 (0.547 – 1.005) 0.010 **
OSBPL9 0.803 (0.671 – 0.962) 0.017 ** 0.818 (0.640 – 1.045) 0.047 **
CPXCR1 0.918 (0.811 – 1.041) 0.183’ 1.030 (0.766 – 1.387) 0.840
SORCS2 1.159 (1.041 – 1.290) 0.006 ** 0.936 (0.752 – 1.166) 0.558
PDC 0.812 (0.679 – 0.970) 0.022 ** 1.068 (0.796 – 1.432) 0.659
C12orf66 0.902 (0.808 – 1.008) 0.069 * 1.007 (0.729 – 1.390) 0.965
SLC38A9 0.919 (0.845 – 1.000) 0.050 * 1.073 (0.894 – 1.289) 0.443
OR10H5 0.846 (0.704 – 1.018) 0.075 * 1.078 (0.826 – 1.407) 0.579
TRIP13 0.881 (0.802 – 0.968) 0.008 ** 0.985 (0.780 – 1.244) 0.901
MRPL52 0.848 (0.767 – 0.939) 0.001 ** 0.865 (0.697 – 1.075) 0.019 **
DUSP21 0.903 (0.807 – 1.011) 0.077 * 0.928 (0.697 – 1.235) 0.609
BRCA1 0.836 (0.764 – 0.915) 0.000 *** 0.884 (0.713 – 1.097) 0.264
ELTD1 1.155 (1.021 – 1.307) 0.021 ** 0.969 (0.772 – 1.216) 0.787
SPG7 1.141 (1.035 – 1.259) 0.008 ** 1.026 (0.840 – 1.255) 0.797
LASS6 0.867 (0.782 – 0.961) 0.006 ** 0.788 (0.631 – 0.984) 0.035 **
DUOX2 1.076 (0.975 – 1.187) 0.141’ 1.039 (0.844 – 1.280) 0.715
Age (>60) 0.154 (0.01953 – 1.225) 0.045 ** 0.562 (0.0354 – 2.392) 0.049 **
Gender 1.048 (0.554 – 1.981) 0.886 1.729 (0.704 – 4.245) 0.231
Stage 1.644 (0.8567 – 3.156) 0.135’ 1.274 (0.494 – 3.286) 0.615
  1. This table shows the univariate and multivariate cox proportional hazard regression analyses of 19 gene signatures and other clinical variables associated with overall survival of CRC patients. [Relevant location: Page 14]