TY - JOUR AU - Sen, Subhojit AU - Block, Kirsten F. AU - Pasini, Alice AU - Baylin, Stephen B. AU - Easwaran, Hariharan PY - 2016 DA - 2016/09/15 TI - Genome-wide positioning of bivalent mononucleosomes JO - BMC Medical Genomics SP - 60 VL - 9 IS - 1 AB - Bivalent chromatin refers to overlapping regions containing activating histone H3 Lys4 trimethylation (H3K4me3) and inactivating H3K27me3 marks. Existence of such bivalent marks on the same nucleosome has only recently been suggested. Previous genome-wide efforts to characterize bivalent chromatin have focused primarily on individual marks to define overlapping zones of bivalency rather than mapping positions of truly bivalent mononucleosomes. SN - 1755-8794 UR - https://doi.org/10.1186/s12920-016-0221-6 DO - 10.1186/s12920-016-0221-6 ID - Sen2016 ER -