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Table 5 Common genes found in the identified subnetworks with at least three gene members across four datasets by using three different approaches

From: GSNFS: Gene subnetwork biomarker identification of lung cancer expression data

GGI PPI
GNFS-greedy [14] GSNFS-GS GSNFS-PN GNFS-greedy [14] GSNFS-GS GSNFS-PN
MAPK1 None MAPK1 MAPK1 EGFR EGFR
MAP2K3 TNFRSF1A MAPK1 MAPK1
MAP2K4 SHC1 TNFRSF1A TNFRSF1A
PRKCA SOS2 MAP3K7
STAT3
  1. All gene members in gene subnetworks with at least three gene members were inspected for the common genes obtained from the identified gene subnetworks across four datasets by using different searching strategies and different network data in subnetwork identification. The genes in italic indicate the important genes in lung cancer