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Table 1 Summary of the main epidemiological variables for the pooled-DNA allelotyping GWASs (A) and validation cohorts (B)

From: A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients

A.

Type

Sex

Pooled-DNA GWAS

Enrolled (Set I)

Enrolled (Set II)

Na

Age, range (years)

Median age (years)

Nb

Age, range (years)

Median age (years)

PSC

Females

40

12–61

31

37

17–52

31

Males

80

9–64

26

74

9–49

26

All

120

9–64

29

111

9–52

28

PBC

Females

420

14–85

53

407

29–80

53

Males

0

0

0

0

0

0

 

420

14–85

53

407

29–80

53

Healthy controls

Females

363

3–88

55

222

25–65

43

Males

361

3–69

22

148

28–65

47

All

724

3–88

50

370

25–65

44

B.

Type

Sex

Individual patient genotyping

Enrolled

N

Age, range (years)

Median age (years)

PSC

Females

41

17–52

31

Males

98

9–64

26

All

139

9–64

29

PBC

Females

443

14–85

54

Males

0

0

0

 

443

14–85

54

Healthy controls

Females

512

23–75

48

Males

422

27–78

48

All

934

23–78

47

  1. Panels indicate the number of patients enrolled in the GWAS (Na) after excluding microarrays that did not meet quality control criteria based on principal component analysis results (Nb) that included validation and replication analyses performed using respective individual patient TaqMan genotyping (N). The range and median values are the ages of cases and controls in the respective groups in years