Fig. 4

Top 3 glucocorticoid sensitive sites, based on magnitude of methylation difference. Increased methylation was observed at GpG sites of (a) GSTM1, (b) MYO3B, and (c) GSTM5 in the ME/CFS GC-Hypersensitive (black) compared to ME/CFS GC-Typical (grey) and Controls (white). * = p ≤0.05, Wilcoxon rank-sum test