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Table 4 Epigenetic loci associated with GC sensitivity in ME/CFS

From: Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Probe ID Targeted gene symbol Mean Beta-value (ME/CFS GC-Hypersensitive) Mean Beta-value (ME/CFS GC-Typical) Mean Beta-value (control) Genic region
cg03484234 PNPLA4 0.595 0.525 0.536 TSS1500
cg04072270 N/A 0.651 0.708 0.715 N/A
cg04438194 N/A 0.199 0.134 0.147 N/A
cg05123845 N/A 0.546 0.601 0.605 N/A
cg05252487 FAM24A 0.289 0.354 0.344 5' UTR
cg05376982 GSTM5 0.609 0.498 0.479 TSS200
cg11680055 GSTM1 0.440 0.318 0.276 TSS200
cg12042203 N/A 0.672 0.618 0.620 N/A
cg14507445 N/A 0.833 0.776 0.773 N/A
cg15059639 MYO3B 0.762 0.636 0.614 Body
cg19196401 DDO 0.520 0.615 0.598 Body
cg19251564 N/A 0.711 0.660 0.654 N/A
cg19763428 PDE1C 0.420 0.362 0.349 Body
  1. Thirteen differentially methylated sites that are associated with glucocorticoid sensitivity in ME/CFS GC-Hypersensitive subjects