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Table 5 Epigenomic regions associated with quality of life

From: Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Gene

Region

R2

FDR

Mean (ME/CFS)

Mean (control)

Beta-difference

GRAMD1A

TSS1500

0.229

4.27e-3

0.357

0.265

0.092

ATP6V0E2

TSS200

0.226

4.27e-3

0.335

0.256

0.079

LOC401431

Gene Body

0.224

4.27e-3

0.347

0.266

0.081

IL6R

Gene Body

0.220

4.27e-3

0.380

0.304

0.076

LOC144571

TSS1500

0.220

4.27e-3

0.314

0.237

0.077

  1. Top 5 regions based on R2 that show a significant relationship between DNA methylation and overall RAND-36 score
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BMC Medical Genomics

ISSN: 1755-8794

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