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Table 5 Epigenomic regions associated with quality of life

From: Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Gene Region R2 FDR Mean (ME/CFS) Mean (control) Beta-difference
GRAMD1A TSS1500 0.229 4.27e-3 0.357 0.265 0.092
ATP6V0E2 TSS200 0.226 4.27e-3 0.335 0.256 0.079
LOC401431 Gene Body 0.224 4.27e-3 0.347 0.266 0.081
IL6R Gene Body 0.220 4.27e-3 0.380 0.304 0.076
LOC144571 TSS1500 0.220 4.27e-3 0.314 0.237 0.077
  1. Top 5 regions based on R2 that show a significant relationship between DNA methylation and overall RAND-36 score