AML subtypes | Number of patients included in analysis | Number of p53-related DEGs |
---|---|---|
Cytogenetic groups | ||
 Normal | 290 | 147* |
 t (15;17) | 34 | 172* |
 t (8;21) | 39 | 202* |
 inv (16) | 37 | 147* |
 11q23 | 10 | 165* |
 -5/7 (q) | 31 | 102* |
 trisomy 8 | 26 | 109* |
 Complex | 23 | 104* |
 t (6;9) | 5 | 176* |
 t (9;22) | 3 | 78 |
 -9(q) | 7 | 88 |
FAB groups | ||
 M0 | 48 | 145* |
 M1 | 136 | 90* |
 M2 | 157 | 37 |
 M3 | 34 | 172* |
 M4 | 108 | 39 |
 M4E | 5 | 185* |
 M5 | 110 | 68* |
 M6 | 9 | 42 |
Molecular mutations | ||
 FLT3-ITD | 132 | 128* |
 FLT3-TKD | 46 | 64 |
 NPM1 | 154 | 151* |
 CEBPA | 33 | 97 |
 NRAS | 44 | 143* |
 KRAS | 4 | 171* |
 EV1 | 28 | 163* |
 RUNX1 | 11 | 143* |
Total number of patients | 607 | Â |