Fig. 3
From: Computational analysis of the mesenchymal signature landscape in gliomas
Survival-prioritized EMO genes. EMO genes (and transcription factors regulating them) were prioritized according to their impact on survival. LASSO Penalized Regression was used for Cox-survival prioritization. a Expression profiles of 20 genes with non-zero regression coefficients: ADAMTS1, BMP2, CD44, CTSS, DST, EFEMP2, EGR1, IRF1, ITGAL, ITGB2, ITGB4, LAMB1, NKX3-2, PDGFA, PPARG, RUNX1, SPI1, SREBF2, TNR, ZEB1. TFs are labeled in green. b Survival analysis based on a multi-gene prognostic index stratification. Age and type (LGG versus GBM) were also included in the model