Table 3 Molecular profile of LGGsa
From: Computational analysis of the mesenchymal signature landscape in gliomas
Total LGGs | Low MS | |
|---|---|---|
Cluster of Clusters (CoC) | ||
COC1 | 50 (40.3%) | 27 (39.1%) |
COC2 | 5 (4%) | 0 (0%) |
COC3 | 43 (34.7%) | 27 (39.1%) |
< NA> | 26 (21%) | 15 (21.7%) |
IDH and 1p/19q codel | ||
IDH wt | 11 (8.9%) | 3 (4.3%) |
IDH mut | 43 (34.7%) | 24 (34.8%) |
IDH mut, 1p/19q codel | 39 (31.5%) | 24 (34.8%) |
< NA> | 31 (25%) | 18 (26.1%) |
Methylation cluster | ||
M1 | 8 (6.5%) | 4 (5.8%) |
M2 | 10 (8.1%) | 9 (13%) |
M3 | 46 (37.1%) | 24 (34.8%) |
M4 | 3 (2.4%) | 0 (0%) |
M5 | 31 (25%) | 17 (24.6%) |
< NA> | 26 (21%) | 15 (21.7%) |
miRNA Cluster | ||
mi1 | 25 (20.2%) | 14 (20.3%) |
mi2 | 69 (55.6%) | 40 (58%) |
mi3 | 2 (1.6%) | 0 (0%) |
mi4 | 2 (1.6%) | 0 (0%) |
<NA> | 26 (21%) | 15 (21.7%) |
RNASeq Cluster | ||
R1 | 29 (23.4%) | 15 (21.7%) |
R2 | 8 (6.5%) | 0 (0%) |
R3 | 12 (9.7%) | 8 (11.6%) |
R4 | 33 (26.6%) | 19 (27.5%) |
< NA> | 42 (33.9%) | 27 (39.1%) |
RPPA Cluster | ||
P1 | 32 (25.8%) | 18 (26.1%) |
P2 | 26 (21%) | 12 (17.4%) |
P3 | 7 (5.6%) | 1 (1.4%) |
P4 | 19 (15.3%) | 13 (18.8%) |
< NA> | 42 (33.9%) | 25 (36.2%) |