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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Large-scale gene network analysis reveals the significance of extracellular matrix pathway and homeobox genes in acute myeloid leukemia: an introduction to the Pigengene package and its applications

Fig. 4

A simple decision tree for distinguishing AML from MDS cases. If the normalized extracellular matrix eigengene of a case is less than -0.001, it is classified as AML. Otherwise, the HOXA&B eigengene determines whether the case is AML (>−0.004) or MDS (≤−0.004). The number of cases classified in each leaf is noted for both the MILE (left) and the BCCA (right) datasets. Only the middle leaf corresponds to MDS. At the fixed thresholds shown above, this tree correctly classified 328 cases (90%) in the MILE dataset (the training set) and 71 cases (96%) in the BCCA dataset (the test set)

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BMC Medical Genomics

ISSN: 1755-8794

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