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Fig. 4 | BMC Medical Genomics

Fig. 4

From: CLImAT-HET: detecting subclonal copy number alterations and loss of heterozygosity in heterogeneous tumor samples from whole-genome sequencing data

Fig. 4

The copy number inference results of different methods on a simulated sample. Major and total copy numbers inferred by CLImAT-HET, OncoSNP-SEQ and CLImAT are compared with the ground truth, respectively. The predefined major and total copy numbers of all segments in simulation study are treated as underlying truth. The results show that CLImAT-HET infers the correct copy numbers for 86% of all segments

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