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Fig. 4 | BMC Medical Genomics

Fig. 4

From: GRMD cardiac and skeletal muscle metabolism gene profiles are distinct

Fig. 4

Diagram of glycolysis is shown, including enzymes whose transcripts were more highly expressed in GRMD (red) or wild type dogs (green). Metabolic transporters are also shown. The information was compiled using various public databases, and the figure was produced using Protein Lounge pathway builder software (ePath3D). The hemoglobin molecule was obtained from the Protein Databank ( The embedded dog illustration showing dystrophic musculature (top left) is an original work of art produced by Dave Carlson ( Note: Common protein symbols are shown, some of which are represented by several different synonyms or have different names for their respective transcripts. For instance, MCP1 and 2 are also called BP44 and BP44L. PFK2 is encoded by PFKFB3

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