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Table 3 Simulation parameters

From: N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

Parameter Description of the parameter Values tested
bg.FC Fold change of dysregulated background mRNAs {1, 1.3, 1.5, 2}
bg.dPct Percentage of dysregulated mRNAs as noise in the background {0, 0.01, 0.05, 0.1, 0.2}
p.S Number of mRNAs randomly chosen in the target pathway {5, 10, [15, 490] by step 25, 500}
p.dPct Percentage of dysregulated mRNAs in the target pathway {(0, 1] by step 0.05}
p.FC Fold change of mRNAs in the target pathway {1.3, 1.5, 2}
p.upPct Percentage of up-regulated mRNAs among dysregulated mRNAs in the target pathways {0, 0.1, 0.2, 0.3, 0.4, 0.5}