Table 3 Simulation parameters

bg.FC

Fold change of dysregulated background mRNAs

{1, 1.3, 1.5, 2}

bg.dPct

Percentage of dysregulated mRNAs as noise in the background

{0, 0.01, 0.05, 0.1, 0.2}

p.S

Number of mRNAs randomly chosen in the target pathway

{5, 10, [15, 490] by step 25, 500}

p.dPct

Percentage of dysregulated mRNAs in the target pathway

{(0, 1] by step 0.05}

p.FC

Fold change of mRNAs in the target pathway

{1.3, 1.5, 2}

p.upPct

Percentage of up-regulated mRNAs among dysregulated mRNAs in the target pathways

{0, 0.1, 0.2, 0.3, 0.4, 0.5}