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Table 4 Top 10 pathways having the largest gene count from enrichment analysis (p-value < 0.05)

From: Integrative information theoretic network analysis for genome-wide association study of aspirin exacerbated respiratory disease in Korean population

Pathway Name Pathway
Id
Source
Name
Gene count Genes in
InnateDB
for this
entity
p-value p-value
(corrected)
Signaling by GPCR 17449 REACTOME 30 1035 9.60E-04 4.54E-02
GPCR ligand binding 19266 REACTOME 20 433 1.95E-05 4.61E-03
G alpha (q) signalling events 13217 REACTOME 13 186 8.92E-06 4.22E-03
Gastrin-CREB signalling pathway via PKC and MAPK 13219 REACTOME 13 212 3.60E-05 5.67E-03
G alpha (i) signalling events 13220 REACTOME 13 231 8.71E-05 8.24E-03
Neuroactive ligand-receptor interaction 416 KEGG 13 275 4.84E-04 3.27E-02
GPCR signaling 16218 INOH 13 293 8.76E-04 4.60E-02
Class A/1 (Rhodopsin-like receptors) 13250 REACTOME 13 307 0.001341054 4.88E-02
Transport of inorganic cations/anions and amino acids/oligopeptides 13174 REACTOME 7 94 7.75E-04 4.58E-02
LPA receptor mediated events 15008 PID NCI 6 46 8.69E-05 1.03E-02