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Table 3 Gene-based association results (p-values) of common variants (MAF ≥ 5%; SNPs and Indels) of genes near the APOE region with CSF biomarker Aβ1-42 with and without adjusting for APOE genotypes

From: Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Gene SNP + Indel SNP
p-value p-value adjusted for APOE genotype p-value p-value adjusted for APOE genotype
BCL3 0.0013 0.0005 0.0019 0.0005
CBLC 0.0006 0.0122 0.0005 0.0128
BCAM 0.0014 0.0132 0.0016 0.0131
PVRL2 <1.0E-05 0.6852 <1.0E-05 0.6665
TOMM40 <1.0E-05 1.0000 <1.0E-05 1.0000
APOE <1.0E-05 0.1380 <1.0E-05 1.0000
APOC1 <1.0E-05 1.0000 <1.0E-05 1.0000
APOC1P1 <1.0R-05 1.000 <1.0E-05 1.0000
APOC4 0.1718 1.000 0.1437 1.0000
APOC2 0.0406 0.0621 0.0152 0.0570
CLPTM1 0.0198 0.0467 0.0331 0.0464
RELB 0.0515 0.6551 0.2485 0.6095