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Table 3 Pathway over-representation analysis of 120 genes associated with interactions between miRNA and methylation

From: Identification of epigenetic interactions between miRNA and DNA methylation associated with gene expression as potential prognostic markers in bladder cancer

Reactome pathway name p-value FDR q-value
Oncogene induced senescence 0.0002 0.019
Deactivation of the beta-catenin transactivating complex 0.0002 0.019
Pre-NOTCH transcription and translation 0.0004 0.023
Oxidative stress induced senescence 0.001 0.025
NCAM1 interactions 0.001 0.025
PIP3 activates AKT signaling 0.002 0.025
PI-3 K cascade:FGFR1 0.002 0.025
PI-3 K cascade:FGFR2 0.002 0.025
PI-3 K cascade:FGFR3 0.002 0.025
PI-3 K cascade:FGFR4 0.002 0.025
PI3K events in ERBB4 signaling 0.002 0.025
PI3K events in ERBB2 signaling 0.002 0.025
Pre-NOTCH expression and processing 0.002 0.025
Cellular senescence 0.002 0.025
PI3K/AKT activation 0.002 0.025
GAB1 signalosome 0.002 0.025
Role of LAT2/NTAL/LAB on calcium mobilization 0.003 0.027
repression of WNT target genes 0.005 0.044
Downstream signaling events of B Cell Receptor (BCR) 0.005 0.047
AKT phosphorylates targets in the cytosol 0.006 0.048
Negative regulation of the PI3K/AKT network 0.006 0.048
Cyclin D associated events in G1 0.007 0.048
G1 phase 0.007 0.048