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Table 3 cis eQTL relationships involving variants close to regions associated with AF via genome-wide association studies

From: Post-operative atrial fibrillation examined using whole-genome RNA sequencing in human left atrial tissue

SNP

Gene

Chromosome

SNP Location

p-value

FDR adjusted p-value

rs60632610

MYOZ1

10

75,415,677

1.7 × 10-14

3.5 × 10-10

rs10894154

CNTN5

11

99,781,954

2.8 × 10-6

0.007

rs4437927

FMO6P

1

170,196,342

6.2 × 10-6

0.01

rs9409797

MIR27B

9

97,276,713

6.5 × 10-6

0.01

rs6590399

CNTN5

11

99,759,525

7.4 × 10-6

0.01

rs8847

RIT1

1

155,259,323

1.0 × 10-5

0.02

rs305043

PAQR5

15

70,088,292

1.8 × 10-5

0.03

rs10908463

RIT1

1

155,286,258

2.2 × 10-5

0.03

rs11264341

GBAP1

1

155,151,493

3.1 × 10-5

0.04

  1. Shown are all significant cis eQTL relationships (at FDR-adjusted p-value < 0.05) between SNPs previously characterized as being associated with AF and genes within 500 kb [23]. For each gene, the most significant eQTL relationship is shown. Variant location is in coordinates from the UCSC hg19 genome annotation
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BMC Medical Genomics

ISSN: 1755-8794

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