Table 1 Predicted novel and known Therapeutic transcription factors
From: In silico identification of potential key regulatory factors in smoking-induced lung cancer
| Symbol | Description | Literature evidence |
|---|---|---|
| CREB1 | Cyclic AMP-responsive element-binding protein 1 | [18,19,20,21] |
| NUCKS1 | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1A, P1 | [22, 23] |
| HOXB4 | Homeobox protein Hox-B4, HOX2F | [24, 25] |
| MYCN | N-myc proto-oncogene protein | [26,27,28] |
| MYC | Myc proto-oncogene protein | [26, 29] |
| PHF8 | Histone lysine demethylase PHF8 | [30, 31] |
| TRIM28 | Transcription intermediary factor 1-beta (TIF1-beta) | [32,33,34] |
| WT1 | Wilms tumor protein | [35,36,37,38] |
| CRX | Cone-rod homeobox protein | New |
| CUX1 | Homeobox protein cut-like 1 | [39,40,41,42] |
| GABP | GA-binding protein | New |
| TCF3 | Transcription factor E2-alpha | New |