In silico identification of potential key regulatory factors in smoking-induced lung cancer

BMC Medical Genomics

Table 1 Predicted novel and known Therapeutic transcription factors

Symbol	Description	Literature evidence
CREB1	Cyclic AMP-responsive element-binding protein 1	[18,19,20,21]
NUCKS1	Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1A, P1	[22, 23]
HOXB4	Homeobox protein Hox-B4, HOX2F	[24, 25]
MYCN	N-myc proto-oncogene protein	[26,27,28]
MYC	Myc proto-oncogene protein	[26, 29]
PHF8	Histone lysine demethylase PHF8	[30, 31]
TRIM28	Transcription intermediary factor 1-beta (TIF1-beta)	[32,33,34]
WT1	Wilms tumor protein	[35,36,37,38]
CRX	Cone-rod homeobox protein	New
CUX1	Homeobox protein cut-like 1	[39,40,41,42]
GABP	GA-binding protein	New
TCF3	Transcription factor E2-alpha	New

ISSN: 1755-8794