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Table 1 Predicted novel and known Therapeutic transcription factors

From: In silico identification of potential key regulatory factors in smoking-induced lung cancer

Symbol Description Literature evidence
CREB1 Cyclic AMP-responsive element-binding protein 1 [18,19,20,21]
NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1A, P1 [22, 23]
HOXB4 Homeobox protein Hox-B4, HOX2F [24, 25]
MYCN N-myc proto-oncogene protein [26,27,28]
MYC Myc proto-oncogene protein [26, 29]
PHF8 Histone lysine demethylase PHF8 [30, 31]
TRIM28 Transcription intermediary factor 1-beta (TIF1-beta) [32,33,34]
WT1 Wilms tumor protein [35,36,37,38]
CRX Cone-rod homeobox protein New
CUX1 Homeobox protein cut-like 1 [39,40,41,42]
GABP GA-binding protein New
TCF3 Transcription factor E2-alpha New