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Table 2 Predicted novel and known therapeutic kinases

From: In silico identification of potential key regulatory factors in smoking-induced lung cancer

Symbol

Description

Literature evidence

MAPK1

Mitogen-activated protein kinase 1 or ERK-2

[47, 48]

IGF1R

Insulin-like growth factor 1 receptor

[49,50,51,52]

RPS6KA1

Ribosomal protein S6 kinase alpha-1 or RSK-1

[53, 54]

ATR

Serine/threonine-protein kinase

[55]

MAPK14

Mitogen-activated protein kinase 14 or MAP kinase p38 alpha

[56, 57]

MAPK3

Mitogen-activated protein kinase 3 or Extracellular signal-regulated kinase 1 (ERK-1)

[58, 59]

MAPK4

Mitogen-activated protein kinase 4 or Extracellular signal-regulated kinase 4 (ERK-4)

[60]

MAPK8

Mitogen-activated protein kinase 8 or Stress-activated protein kinase JNK1 or c-Jun N-terminal kinase 1

[61, 62]

PRKCZ

Protein kinase C zeta type

[63]

INSR

Insulin receptor

[3]

PRKAA1

5′-AMP-activated protein kinase catalytic subunit alpha-1

New