Table 2 Predicted novel and known therapeutic kinases
From: In silico identification of potential key regulatory factors in smoking-induced lung cancer
Symbol | Description | Literature evidence | ||
|---|---|---|---|---|
MAPK1 | Mitogen-activated protein kinase 1 or ERK-2 | |||
IGF1R | Insulin-like growth factor 1 receptor | |||
RPS6KA1 | Ribosomal protein S6 kinase alpha-1 or RSK-1 | |||
ATR | Serine/threonine-protein kinase | [55] | ||
MAPK14 | Mitogen-activated protein kinase 14 or MAP kinase p38 alpha | |||
MAPK3 | Mitogen-activated protein kinase 3 or Extracellular signal-regulated kinase 1 (ERK-1) | |||
MAPK4 | Mitogen-activated protein kinase 4 or Extracellular signal-regulated kinase 4 (ERK-4) | [60] | ||
MAPK8 | Mitogen-activated protein kinase 8 or Stress-activated protein kinase JNK1 or c-Jun N-terminal kinase 1 | |||
PRKCZ | Protein kinase C zeta type | [63] | ||
INSR | Insulin receptor | [3] | ||
PRKAA1 | 5′-AMP-activated protein kinase catalytic subunit alpha-1 | New | ||