Table 2 Predicted novel and known therapeutic kinases
From: In silico identification of potential key regulatory factors in smoking-induced lung cancer
| Symbol | Description | Literature evidence | ||
|---|---|---|---|---|
| MAPK1 | Mitogen-activated protein kinase 1 or ERK-2 | [47, 48] | ||
| IGF1R | Insulin-like growth factor 1 receptor | [49,50,51,52] | ||
| RPS6KA1 | Ribosomal protein S6 kinase alpha-1 or RSK-1 | [53, 54] | ||
| ATR | Serine/threonine-protein kinase | [55] | ||
| MAPK14 | Mitogen-activated protein kinase 14 or MAP kinase p38 alpha | [56, 57] | ||
| MAPK3 | Mitogen-activated protein kinase 3 or Extracellular signal-regulated kinase 1 (ERK-1) | [58, 59] | ||
| MAPK4 | Mitogen-activated protein kinase 4 or Extracellular signal-regulated kinase 4 (ERK-4) | [60] | ||
| MAPK8 | Mitogen-activated protein kinase 8 or Stress-activated protein kinase JNK1 or c-Jun N-terminal kinase 1 | [61, 62] | ||
| PRKCZ | Protein kinase C zeta type | [63] | ||
| INSR | Insulin receptor | [3] | ||
| PRKAA1 | 5′-AMP-activated protein kinase catalytic subunit alpha-1 | New | ||