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Table 2 Predicted novel and known therapeutic kinases

From: In silico identification of potential key regulatory factors in smoking-induced lung cancer

Symbol Description Literature evidence
MAPK1 Mitogen-activated protein kinase 1 or ERK-2 [47, 48]
IGF1R Insulin-like growth factor 1 receptor [49,50,51,52]
RPS6KA1 Ribosomal protein S6 kinase alpha-1 or RSK-1 [53, 54]
ATR Serine/threonine-protein kinase [55]
MAPK14 Mitogen-activated protein kinase 14 or MAP kinase p38 alpha [56, 57]
MAPK3 Mitogen-activated protein kinase 3 or Extracellular signal-regulated kinase 1 (ERK-1) [58, 59]
MAPK4 Mitogen-activated protein kinase 4 or Extracellular signal-regulated kinase 4 (ERK-4) [60]
MAPK8 Mitogen-activated protein kinase 8 or Stress-activated protein kinase JNK1 or c-Jun N-terminal kinase 1 [61, 62]
PRKCZ Protein kinase C zeta type [63]
INSR Insulin receptor [3]
PRKAA1 5′-AMP-activated protein kinase catalytic subunit alpha-1 New