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Table 3 Predicted PPI- hubs

From: In silico identification of potential key regulatory factors in smoking-induced lung cancer

Symbol Description Literature evidence
MEPCE 7SK snRNA methylphosphate capping enzyme or Bicoid-interacting protein 3 homolog (Bin3 homolog) [3]
CDK1 Cyclin-dependent kinase 1 [65]
PRKCA Protein kinase C alpha type or PKC-A [66]
COPS5 COP9 signalosome complex subunit 5 [67, 68]
GSK3B Glycogen synthase kinase-3 beta [69]
BRCA1 Breast cancer type 1 susceptibility protein [70, 71]
EP300 Histone acetyltransferase p300 or p300 HAT [72, 73]
PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [74, 76]