Table 3 Predicted PPI- hubs
From: In silico identification of potential key regulatory factors in smoking-induced lung cancer
| Symbol | Description | Literature evidence |
|---|---|---|
| MEPCE | 7SK snRNA methylphosphate capping enzyme or Bicoid-interacting protein 3 homolog (Bin3 homolog) | [3] |
| CDK1 | Cyclin-dependent kinase 1 | [65] |
| PRKCA | Protein kinase C alpha type or PKC-A | [66] |
| COPS5 | COP9 signalosome complex subunit 5 | [67, 68] |
| GSK3B | Glycogen synthase kinase-3 beta | [69] |
| BRCA1 | Breast cancer type 1 susceptibility protein | [70, 71] |
| EP300 | Histone acetyltransferase p300 or p300 HAT | [72, 73] |
| PIN1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | [74, 76] |