Fig. 1

Genetic intratumor heterogeneity, homogeneity, and phylogeny in a patient with gastric carcinoma. a-b The biopsy sites and regions harvested clockwise from the surgically resected gastric carcinoma. c Phylogenetic relationships among six tumor regions. d Distribution of 382 exonic nonsynonymous SNVs in six primary tumor regions, these mutations are mapped to 35 trunk mutations (54.97%, 210/382), 17 branch mutations (16.84%, 64/382), and 108 private mutations (28.27%, 108/382). The heat map reveals the presence (red) or absence (blue) of a mutation in each region of sample. The color bars above the heat map give a value (Var1) that indicates the number of samples involving the same mutation site