Fig. 2

Common mutation proportions between regional samples and the number of samples sufficient to identify a majority of trunk mutations. a The proportion of stopgains shared by any one to six samples in the respective samples. b The proportion of synonymous mutations shared by any one to six samples in the respective samples. c The proportion of nonsynonymous mutations shared by any one to six samples in respective samples. The x-axis indicates the volume of samples needed to result in shared mutations. d-f The proportion of trunk mutations (n = 35) of the mutations shared by any one to six samples. The x-axis indicates the volume of samples needed to result in shared mutations. (d: stopgains, e: synonymous SNVs, f: nonsynonymous SNVs). Two-region sampling (83%) or three-region sampling (89%) may be a cost-effective strategy to obtain a majority of trunk mutations in gastric carcinoma