Table 1 Nucleotide substitution rates and divergence times for the VP1 genes of GI (n = 102, 1623 nt) and GII (n = 374, 1623 nt) NoVs in Chinaa
From: Genomic diversity and phylogeography of norovirus in China
Genotype | Molecular clock | Nucleotide substitution rate (10–3 substitutions/site/year) | TMRCA by: | |
|---|---|---|---|---|
No. of year | Date (range) | |||
GI | Strict | 1.22 (0.67, 1.80) | 287.0 (159.1, 454.1) | 1727.0 (1559.9, 1854.9) |
GI | UCLN | 1.69 (0.79, 2.73) | 275.4 (112.1, 485.0) | 1738.6 (1529.0, 1901.9) |
GI | UCED | 1.68 (0.88, 2.62) | 276.9 (100.2, 515.1) | 1737.1 (1498.9, 1913.8) |
GII | Strict | 2.69 (2.12, 3.31) | 191.3 (133.4, 253.3) | 1823.7 (1761.7, 1881.6) |
GII | UCLN | 4.56 (3.39, 5.78) | 172.3 (74.0, 304.4) | 1842.7 (1710.6, 1941.0) |
GII | UCED | 4.47 (3.47, 5.50) | 151.4 (65.5, 280.1) | 1863.6 (1734.9, 1949.5) |