Fig. 1

The process of establishing haplotypes and distinguishing between balanced and structurally normal chromosomes embryos through PGH analysis. Informative SNPs should be heterozygous in the carrier, and homozygous in the carrier’s partner and carrier’s family member. These SNPs were used to establish the haplotypes of the breakpoint regions, the whole chromosomes involved in the translocation and the corresponding normal homologous chromosomes in the couple, reference and embryos