Fig. 2

a The genealogic tree in family3. b The peripheral blood karyotype of carrier, the translocation was inherited from her father. c Based on the genetic screening of 23-pairs chromosomes, embryo-1 and embryo-6 were identified as balanced or normal embryos, embryo-2 was identified as unbalanced embryo. d The haplotypes including the two breakpoint regions, the two whole chromosomes involved in the translocation and the two corresponding normal homologous chromosomes in the couple, reference who has the same translocation and embryos were shown. The recombination was identified outside the breakpoints. The colorful histograms represented haplotypes, in the embryos the gray column represented the haplotype that was inherited from the normal parent and in the carrier’s family number the gray column represented the haplotype that wasn’t passed on to the carrier, the other different colorful histograms represented different haplotypes. The PGH result indicated embryo-6 was a translocation carrier embryo and embryo-1 was a structurally normal embryo